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Determination of Water Content and Dynamic Vapor Sorption Using Gravimetric Methods, Karl Fischer Titration and Thermal Analysis
Monday, June 20, 2016
Matthias Wagner
Virtually all materials interact with water. Accurate determination of a product’s water content and mechanism of water–solid interactions is required to define suitable processing, packaging, storage...
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Effective Techniques for Maintaining Test Sieves
Friday, August 09, 2019
Candace Blaker
As a sensitive technical instrument, it is essential to take proper care of sieves. If a sieve falls out of specification, it could adversely affect quality standards; however, a well-maintained sieve...
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Electrochemical Determination of Acetaminophen Using Gold Nanoparticles–Multiwall Carbon Nanotubes Modified Glassy Carbon Electrode
Monday, December 15, 2014
Youyuan Peng
Zhifu Zheng
Since their discovery in 1991, carbon nanotubes (CNTs) have been extensively studied for use in emitting devices, energy storage, sensor field, and biological and biomedical applications.
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Ensuring Biopharmaceutical Data Integrity in a Changing R&D Landscape: How Cloud-Based Solutions Overcome Big Data Challenges
Wednesday, December 12, 2018
Trish Meek
Cloud-based informatics platforms are streamlining biopharmaceutical R&D and accelerating the process of bringing new drugs to market.
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Failure Analysis of Rubber Materials Using Pyrolysis-GC/MS
Wednesday, February 14, 2018
Rojin Belganeh
William Pipkin
Pyrolysis GC/MS has a wide variety of applications for identifying the organic composition of unknown samples by providing detail information about the compounds present in a sample.
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Fume Hoods and Cabinets
Friday, May 19, 2017
Biological safety cabinets and fume hoods protect samples, personnel and the laboratory environment from harsh chemicals or infectious substances.
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GC/VUV: A Novel Tool for the Identification and Quantitation of Gas-Phase Analytes
Monday, February 19, 2018
Paul Johnson
VUV spectroscopy has unique capabilities that address many of the challenges inherent to GC separations.
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High-Throughput Drug Screening of Multicellular Tumor Spheroids
Tuesday, September 27, 2016
Ana Maria P. Pardo
Hannah J. Gitschier
David H. Randle
Terry Riss
Three-dimensional (3-D) culture models are increasingly being used for drug discovery in oncology, as they better represent the complexity of the in vivo microenvironment of solid tumors.
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High-Throughput VOC and Inorganic Gas Analysis: Automated SIFT-MS
Friday, January 20, 2017
Mark J. Perkins
Vaughan S. Langford
Murray J. McEwan
A sensitive technique called selected ion flow tube mass spectrometry (SIFT-MS) allows the direct, real-time monitoring of inorganic gases and volatile organic compounds (VOCs), with no need to ...
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How Visualization and Analytics Help Scientists Make Better Decisions Faster
Friday, May 11, 2018
Tom Oldfield
Robert D. Brown
Artificial intelligence. Machine learning. Automation. As these technologies become more widely adopted among life sciences companies in hopes of better innovation and faster drug development, it is ...
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Impact of Weighing Accuracy and Data Integrity in Forensic Drug Analysis
Friday, November 10, 2017
Tucker Rubino
Klaus Fritsch
Thomas Rohrer
To stay compliant with ever-changing regulations and withstand any challenge in court, it is critical for managers and scientists in forensic laboratories to be well-informed about the key issues ...
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Improving the Crystallization Process for Optimal Drug Development
Friday, March 28, 2014
Michael Collazo
Soheila Vaezeslami
Sarah Burl
Macromolecular X-ray crystallography is an important and powerful technique in drug discovery. Studying the specific interactions of a particular drug with its protein target at the atomic level can ...
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Individual Cell Analysis for Protein Expression and Cell Health Markers
Tuesday, March 21, 2017
Robin T. Clark
The Muse instrument uses microcapillary fluidics and preoptimized reagents to create an inexpensive, compact, portable cell analyzer that requires minimal setup and no expertise to operate.
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Isothermal Titration Calorimetry: An Indispensable Tool for Biological Pathway Research and Drug Development
Monday, October 02, 2017
Verna Frasca
As our knowledge of the genetic and molecular basis of disease continues to grow, drug development programs focus increasingly on those proteins associated with disease states.
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Long-Range Genomics Is Reviving a Lost Art
Wednesday, July 26, 2017
Chris Boles
The instrument described here was designed to treat DNA gently enough that users can prepare libraries of extremely large fragments directly from blood samples, bacterial and tissue cultures, or other...
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Natural Product Drug Discovery From Marine Organisms With Advanced UPLC and MS Technology
Wednesday, May 22, 2019
Espen Hansen
A marine bioprospecting project demonstrated the use of MS/MS-based molecular networking as a dereplication strategy to identify known compounds, their analogs, and related compounds.
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NGS Library Validation Using Automated Capillary Gel Electrophoresis
Friday, November 11, 2016
Varouj Amirkhanian
Eric Tsai
Jemmie Chang
Alice Lin
Next-generation sequencing (NGS) is widely used in genomics, epigenetics and transcriptomics, etc., and also in such clinical diagnostics applications as cancer screening and drug development.
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Product Contamination Visualization and Identification Using FTIR Microspectroscopy
Friday, September 29, 2017
David W. Schiering
Anthony W. Didomenico
John A. Seelenbinder
The identification of surface contamination particles on products is demonstrated using a new FTIR microspectroscopy accessory.
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Proper Monitoring of Refrigerators and Freezers to Protect Valuable Biomedical Inventory
Friday, January 20, 2017
Rob Fusco
Best practices for cold storage must be followed to protect valuable samples. Important goals are to avoid degradation, which stems from high and low temperature extremes, and prevent loss of potency ...
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Quantitative Nanoparticle Analysis Based on Resistive Pulse Sensing
Friday, June 24, 2016
Andrew N. Cleland
Jean-Luc Fraikin
Peter Meinhold
Franklin Monzon
Nanoparticle analysis is becoming a central part of pharmaceutical development.
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